Anti-ADRB2 antibody produced in rabbit
SIGMA/SAB4500577 - affinity isolated antibody
Synonym: ADRBR; B2AR; BAR; BETA2AR; β-2 adrenergic receptor; β-2 adrenoceptor; β-2 adrenoreceptor; ADRB2; ADRB2R
Product Type: Chemical
Immunofluorescence Anti-ADRB2: Cat. No. SAB4500577: Immunofluorescence of NIH-3T3 cells using Anti-ADRB2 antibody. Cells on the left were treated with the Anti-ADRB2 antibody. Cells on the right (negative control) were treated with both Anti-ADRB2 antibody and the synthesized immunogen peptide.
Western Blotting Anti-ADRB2: Cat. No. SAB4500577: Immunoblotting analysis of extracts from HeLa cells, using Anti-ADRB2 antibody. The lane on the left was treated with the Anti-ADRB2 antibody. The lane on the right (negative control) was treated with both Anti-ADRB2 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 46 kDa |
| NCBI accession no. | P07550   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P07550 |
| Biochem/physiol Actions: | Adrenoceptor β 2/β2 adrenergic receptor (ADRB2) binding to agonist activates Gs protein. Variation in the ADRB2 gene is involved in blood pressure (BP) and body mass index (BMI). ADRB2 is associated with nasopharyngeal carcinoma. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Adrenoceptor β 2/β2 adrenergic receptor (ADRB2), a transmembrane protein, belongs to the superfamily of G-protein coupled receptors (GPCRs). This protein is expressed in skeletal muscle, mast cells, lymphocytes, airway smooth muscle, epithelial and endothelial cells of the lung, the smooth muscle of blood vessels, oral and skin keratinocytes. It comprises seven transmembrane domains and three extracellular and three intracellular loops. ADRB2 gene is located on human chromosome 5q32. Anti-ADRB2 Antibody detects endogenous levels of total ADRB2 protein. |
| General description: | Anti-ADRB2 Antibody detects endogenous levels of total ADRB2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ADRB2. Immunogen Range: 201-250 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |