Anti-EPHB1 antibody produced in rabbit
SIGMA/SAB4500776 - affinity isolated antibody
Synonym: ELK; EPB1; EPHT2; EPTH2; Eph receptor B1
MDL Number: MFCD02096314
Product Type: Chemical
Immunohistochemistry Anti-EPHB1: Cat. No. SAB4500776: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-EPHB1 antibody. Cells on the left were treated with the Anti-EPHB1 antibody. Cells on the right (negative control) were treated with both Anti-EPHB1 antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-EPHB1: Cat. No. SAB4500776: Immunofluorescence of NIH-3T3 cells using Anti-EPHB1 antibody. Cells on the left were treated with the Anti-EPHB1 antibody. Cells on the right (negative control) were treated with both Anti-EPHB1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 109 kDa |
| NCBI accession no. | P54762   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | P54762 |
| Biochem/physiol Actions: | EPHB1(ephrin type-B receptor 1) participates in carcinogenesis of RCC (renal cell carcinoma). It plays a major role in the growth of nervous and vascular system. It acts as a biomarker for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-EPHB1 Antibody detects endogenous levels of total EPHB1 protein. |
| General description: | EPHB1(ephrin type-B receptor 1) belongs to the Eph gene family of receptor tyrosine kinases. It is present in venous endothelial cells during embryonic development to adulthood. It is located on human chromosome 3q22.2. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human EPHB1/2/3. Immunogen Range: 631-680 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |