Anti-LMTK2 antibody produced in rabbit
SIGMA/SAB4500900 - affinity isolated antibody
Synonym: Apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; Kinase/
MDL Number: MFCD06798864
Product Type: Chemical
Immunohistochemistry Anti-LMTK2: Cat. No. SAB4500900: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-LMTK2 antibody. Cells on the left were treated with the Anti-LMTK2 antibody. Cells on the right (negative control) were treated with both Anti-LMTK2 antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-LMTK2: Cat. No. SAB4500900: Immunofluorescence of HepG2 cells using Anti-LMTK2 antibody. Cells on the left were treated with the Anti-LMTK2 antibody. Cells on the right (negative control) were treated with both Anti-LMTK2 antibody and the synthesized immunogen peptide.
Western Blotting Anti-LMTK2: Cat. No. SAB4500900: Immunoblotting analysis of extracts from LOVO cells, using Anti-LMTK2 antibody. The lane on the left was treated with the Anti-LMTK2 antibody. The lane on the right (negative control) was treated with both Anti-LMTK2 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 164 kDa |
| NCBI accession no. | Q8IWU2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q8IWU2 |
| Application: | Anti-LMTK2 antibody has been used in western blotting. |
| Biochem/physiol Actions: | Lemur tyrosine kinase 2 (LMTK2) participates in endosomal membrane trafficking and neuronal physiology. It also participates in the differentiation of tissues and acts as a negative regulator of nerve growth factor (NGF)-induced neuronal differentiation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-LMTK2 antibody detects endogenous levels of total LMTK2 protein. |
| General description: | Lemur tyrosine kinase 2 (LMTK2) is a serine/threonine kinase, located in endosomal compartments. It is also termed as BREK (brain-enriched kinase), AATYK-2 (apoptosis-associated tyrosine kinase 2), cdk5, KPI-2 and Cprk. It is expressed at high levels in the plasma membrane. LMTK2 consists of 1503 amino acids and is located on human chromosome 7q21. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human LMTK2. Immunogen Range: 651-700 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |