Anti-MAST3 antibody produced in rabbit
SIGMA/SAB4500930 - affinity isolated antibody
Synonym: KIAA0561; MAST3; Microtubule-
Product Type: Chemical
Western Blotting Anti-MAST3: Cat. No. SAB4500930: Immunoblotting analysis of extracts from Jurkat cells, using Anti-MAST3 antibody. The lane on the left was treated with the Anti-MAST3 antibody. The lane on the right (negative control) was treated with both Anti-MAST3 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 143 kDa |
| NCBI accession no. | O60307   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | O60307 |
| Biochem/physiol Actions: | Microtubule associated serine/threonine kinase 3 (MAST3) modulates the activity of nuclear factor κ-B (NF-κB). It may have a role in inflammatory pathways. Knockdown of MAST3 has been shown to reduce NF-κB activity, which is dependent on toll-like receptor-4. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-MAST3 Antibody detects endogenous levels of total MAST3 protein. Microtubule associated serine/threonine kinase 3 (MAST3) belongs to the MAST kinase family. It is composed of 1309 amino acids. The MAST3 gene is 53.9kb long and has 27 exons. It is localized on human chromosome 19p13.11. MAST3 possesses four α-helix bundles having various domains, including a protein kinase domain and a PDZ domain. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MAST3. Immunogen Range: 1031-1080 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |