Anti-FLT3 antibody produced in rabbit
SIGMA/SAB4500961 - affinity isolated antibody
Synonym: CD135 antigen; STK-1; Stem cell tyrosine kinase 1; Tyrosine-protein kinase receptor FLT3
MDL Number: MFCD01864666
Product Type: Chemical
Western Blotting Anti-FLT3: Cat. No. SAB4500961: Immunoblotting analysis of extracts from LOVO cells, using Anti-FLT3 antibody. The lane on the left was treated with the Anti-FLT3 antibody. The lane on the right (negative control) was treated with both Anti-FLT3 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 112 kDa |
| NCBI accession no. | P36888   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P36888 |
| Biochem/physiol Actions: | Mutation in FLT3 (Fms-like tyrosine kinase) results in acute myeloid leukemia and it also induces warburg effect and offers therapeutic sensitivity to glycolytic inhibition. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-FLT3 antibody detects endogenous levels of total FLT3 protein. |
| General description: | FLT3 (Fms-like tyrosine kinase) is a member of tyrosine kinase (RTK) family. It has an extracellular domain consisting of five immunoglobulin-like domains and an intracellular kinase domain interrupted by a kinase insert. It is located on human chromosome 13q12. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FLT3. Immunogen Range: 565-614 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |