Anti-GABA-B Receptor antibody produced in rabbit
SIGMA/SAB4501062 - affinity isolated antibody
Synonym: G protein-coupled receptor 51; GABA-B RECEPTOR; GABABR2; GPR51; R2 SUBUNIT
Product Type: Chemical
Immunohistochemistry Anti-GABA-B Receptor: Cat. No. SAB4501062: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-GABA-B Receptor antibody. Cells on the left were treated with the Anti-GABA-B Receptor antibody. Cells on the right (negative control) were treated with both Anti-GABA-B Receptor antibody and the synthesized immunogen peptide.
Western Blotting Anti-GABA-B Receptor: Cat. No. SAB4501062: Immunoblotting analysis of extracts from HeLa cells, using Anti-GABA-B Receptor antibody. The lane on the left was treated with the Anti-GABA-B Receptor antibody. The lane on the right (negative control) was treated with both Anti-GABA-B Receptor antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 108 kDa |
| NCBI accession no. | Q9UBS5   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q9UBS5 |
| Biochem/physiol Actions: | The γ-aminobutyric acid type B (GABAB) is essential for the initiation by agonists like GABA (gamma-aminobutyric acid ). GABAB receptors participates in response habituation. In the visual cortex, GABAB is also involved in the initiation of orientation tuning in conjunction with GABAA receptors. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-GABA-B Receptor Antibody detects endogenous levels of total GABA-B Receptor protein. |
| General description: | The γ-aminobutyric acid type B (GABAB) receptor is coded by the GABBR1 gene. It has 22 exons and spans at least 18 kb. GABAB gene is present between an olfactory receptor gene cluster downstream and the HLA (human leukocyte antigen) class I region upstream. It is mapped to human chromosome 6p22. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GABA-B Receptor. Immunogen Range: 871-920 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |