Anti-LATS1 antibody produced in rabbit
SIGMA/SAB4501145 - affinity isolated antibody
Synonym: Kinase phosphorylated during mitosis protein; Large tumor suppressor homolog 1; Serine/
Product Type: Chemical
Immunohistochemistry Anti-LATS1: Cat. No. SAB4501145: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-LATS1 antibody. Cells on the left were treated with the Anti-LATS1 antibody. Cells on the right (negative control) were treated with both Anti-LATS1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 126 kDa |
| NCBI accession no. | O95835   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | O95835 |
| Biochem/physiol Actions: | The LATS1 (large tumor suppressor kinase 1) protein repress the multiplication and invasion of cervical cancer. It acts as a cell cycle inhibitor. Low level expression of LATS1 is associated with the progression and prognosis of glioma. It is a tumor suppressor gene, thereby it participates in various mitotic processes. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-LATS1 Antibody detects endogenous levels of total LATS1 protein. |
| General description: | The LATS1 (large tumor suppressor kinase 1) gene encodes a serine/threonine kinase and is located on human chromosome 6q24-25. It is present in the mitotic apparatus. It is also called as WARTS. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human LATS1/2. Immunogen Range: 1041-1090 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |