Anti-LAMA1 antibody produced in rabbit
SIGMA/SAB4501255 - affinity isolated antibody
Synonym: LAMA; LAMA1; Laminin A chain; Laminin subunit α-1
Product Type: Chemical
Immunofluorescence Anti-LAMA1: Cat. No. SAB4501255: Immunofluorescence of COS7 cells using Anti-LAMA1 antibody. Cells on the left were treated with the Anti-LAMA1 antibody. Cells on the right (negative control) were treated with both Anti-LAMA1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 337 kDa |
| NCBI accession no. | P25391   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| immunofluorescence: 1:100-1:500 | |
| UniProt accession no. | P25391 |
| Application: | Anti-LAMA1, C-Terminal antibody has been used in western blotting. |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Biochem/physiol Actions: | LAMA1 (laminin subunit α 1) participates in several diseases like cancer, infections, inflammatory diseases and autoimmune disorders. Mutations in LAMA1 result in cerebellar dysplasia and cysts with and without retinal dystrophy. LAMA1 is also essential in the assembly of basement membrane and early growth of embryo. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-LAMA1 Antibody detects endogenous levels of total LAMA1 protein. |
| General description: | Laminins are extracellular matrix proteins. The LAMA1 (laminin subunit α 1) gene is mapped to chromosome 18p11. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human LAMA1. Immunogen Range: 2501-2550 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |