Anti-MGLUR7 antibody produced in rabbit
SIGMA/SAB4501325 - affinity isolated antibody
Synonym: GPRC1G; GRM7; MGLUR7; mGluR7; otein name Metabotropic glutamate receptor 7
Product Type: Chemical
Immunohistochemistry Anti-MGLUR7: Cat. No. SAB4501325: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-MGLUR7 antibody. Cells on the left were treated with the Anti-MGLUR7 antibody. Cells on the right (negative control) were treated with both Anti-MGLUR7 antibody and the synthesized immunogen peptide.
Western Blotting Anti-MGLUR7: Cat. No. SAB4501325: Immunoblotting analysis of extracts from HuvEc cells, using Anti-MGLUR7 antibody. The lane on the left was treated with the Anti-MGLUR7 antibody. The lane on the right (negative control) was treated with both Anti-MGLUR7 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 102 kDa |
| NCBI accession no. | Q14831   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q14831 |
| Biochem/physiol Actions: | The gene coding MGLUR7 (glutamate metabotropic receptor 7) is associated with autism. GRM7 participates in the initiation of glutamate receptor. It also participates in schizophrenia and bipolar disorder. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein. MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human mGluR7. Immunogen Range: 866-915 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |