Anti-Acetyl-CoA Carboxylase, N-Terminal antibody produced in rabbit
SIGMA/SAB4501395 - affinity isolated antibody
Synonym: ACAC; ACACA; ACC-α; ACCA; Acetyl-CoA carboxylase 1
Product Type: Chemical
Immunohistochemistry Anti-Acetyl-CoA Carboxylase: Cat. No. SAB4501395: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-Acetyl-CoA Carboxylase antibody. Cells on the left were treated with the Anti-Acetyl-CoA Carboxylase antibody. Cells on the right (negative control) were treated with both Anti-Acetyl-CoA Carboxylase antibody and the synthesized immunogen peptide.
Western Blotting Anti-Acetyl-CoA Carboxylase: Cat. No. SAB4501395: Immunoblotting analysis of extracts from NIH-3T3 cells, treated with PMA 125ng/ml 15′, using Anti-Acetyl-CoA Carboxylase antibody. The lane on the left was treated with the Anti-Acetyl-CoA Carboxylase antibody. The lane on the right (negative control) was treated with both Anti-Acetyl-CoA Carboxylase antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 265 kDa |
| NCBI accession no. | Q13085   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q13085 |
| Biochem/physiol Actions: | Acetyl-CoA carboxylase 1 (ACC1) catalyzes the rate-limiting step in de novo fatty acid biosynthesis. Acetyl-CoA is carboxylated to malonyl-CoA with the help of acetyl-CoA carboxylase (ACACA) in the fatty acid synthesis pathway. ACC1 is essential for the assembly of invadopodia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Acetyl-CoA carboxylase 1 (ACC1) is a cytosolic enzyme. It is located on human chromosome 17q12. |
| General description: | Anti-Acetyl-CoA Carboxylase Antibody detects endogenous levels of total Acetyl-CoA Carboxylase protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Acetyl-CoA Carboxylase. Immunogen Range: 46-95 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |