Anti-KCNJ5 antibody produced in rabbit
SIGMA/SAB4501633 - affinity isolated antibody
Synonym: G protein-activated inward rectifier potassium channel 4; GIRK4; Inward rectifier K(+) channel Kir3.4; Potassium channel; inwardly rectifying subfamily J member 5
Product Type: Chemical
Immunofluorescence Anti-KCNJ5: Cat. No. SAB4501633: Immunofluorescence of A549 cells using Anti-KCNJ5 antibody. Cells on the left were treated with the Anti-KCNJ5 antibody. Cells on the right (negative control) were treated with both Anti-KCNJ5 antibody and the synthesized immunogen peptide.
Western Blotting Anti-KCNJ5: Cat. No. SAB4501633: Immunoblotting analysis of extracts from HeLa cells, using Anti-KCNJ5 antibody. The lane on the left was treated with the Anti-KCNJ5 antibody. The lane on the right (negative control) was treated with both Anti-KCNJ5 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 47 kDa |
| NCBI accession no. | P48544   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunofluorescence: 1:100-1:500 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P48544 |
| Biochem/physiol Actions: | KCNJ5 (potassium voltage-gated channel subfamily J member 5) is associated with aldosteronism, a major cause of secondary hypertension. Mutated KCNJ5 gene affects the polarization of plasma membrane and permit sodium and calcium inflow into the cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-KCNJ5 Antibody detects endogenous levels of total KCNJ5 protein. KCNJ5 (potassium voltage-gated channel subfamily J member 5) is an inwardly rectifying potassium channel, which is also termed as GIRK4 (G protein-coupled inward rectifier K+ channel 4). It is expressed in the cerebral cortex. This gene is mapped to human chromosome 11q24. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human KCNJ5. Immunogen Range: 370-419 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |