Anti-Keratin 17 antibody produced in rabbit
SIGMA/SAB4501662 - affinity isolated antibody
Synonym: CK-17; Cytokeratin-17; K17; Keratin type I cytoskeletal 17
Product Type: Chemical
Immunohistochemistry Anti-Keratin 17: Cat. No. SAB4501662: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-Keratin 17 antibody. Cells on the left were treated with the Anti-Keratin 17 antibody. Cells on the right (negative control) were treated with both Anti-Keratin 17 antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-Keratin 17: Cat. No. SAB4501662: Immunofluorescence of HepG2 cells using Anti-Keratin 17 antibody. Cells on the left were treated with the Anti-Keratin 17 antibody. Cells on the right (negative control) were treated with both Anti-Keratin 17 antibody and the synthesized immunogen peptide.
Western Blotting Anti-Keratin 17: Cat. No. SAB4501662: Immunoblotting analysis of extracts from HuvEc cells, using Anti-Keratin 17 antibody. The lane on the left was treated with the Anti-Keratin 17 antibody. The lane on the right (negative control) was treated with both Anti-Keratin 17 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 48 kDa |
| NCBI accession no. | Q04695   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q04695 |
| Application: | Anti-Keratin 17, C-Terminal antibody has been used in immunohistochemical staining. |
| Biochem/physiol Actions: | Keratin 17/cytokeratin 17 (CK17) plays a major role in the development of various human malignancies. It acts as a biomarker in endocervical glandular neoplasia. CK17 is involved in the development of cell and sizing of keratinocytes. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Keratin 17 antibody detects endogenous levels of total Keratin 17 protein. |
| General description: | Keratin 17/cytokeratin 17 (CK17) is a basal/myoepithelial cell keratin. It is expressed in the respiratory tract, urinary tract and various glands. CK17 is a member of the acidic type I CK family. It is mapped to human chromosome 17q21. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Keratin 17. Immunogen Range: 381-430 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |