Anti-Keratin 19 antibody produced in rabbit
SIGMA/SAB4501670 - affinity isolated antibody
Synonym: CK-19; Cytokeratin-19; K19; KRT19; Keratin type I cytoskeletal 19
MDL Number: MFCD02263565
Product Type: Chemical
Immunohistochemistry Anti-Keratin 19: Cat. No. SAB4501670: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-Keratin 19 antibody. Cells on the left were treated with the Anti-Keratin 19 antibody. Cells on the right (negative control) were treated with both Anti-Keratin 19 antibody and the synthesized immunogen peptide.
Western Blotting Anti-Keratin 19: Cat. No. SAB4501670: Immunoblotting analysis of extracts from LOVO cells, using Anti-Keratin 19 antibody. The lane on the left was treated with the Anti-Keratin 19 antibody. The lane on the right (negative control) was treated with both Anti-Keratin 19 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 44 kDa |
| NCBI accession no. | P08727   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P08727 |
| Biochem/physiol Actions: | Cytokeratin 19 (KRT19) plays a major role in structural rigidity and multipurpose scaffolds. Overexpression of this gene in various cancers may participate in tumorigenic transformation. It may modulate signaling pathways and mediate cell apoptosis, cell cycle arrest, invasion and metastasis. KRT19 plays a vital role in the cancer stemness of hepatocellular carcinoma (HCC). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Keratin 19 Antibody detects endogenous levels of total Keratin 19 protein. |
| General description: | Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein with a α-helical central domain. It belongs to the acidic type I cytokeratin family of proteins (KRTs). This gene is mapped to human chromosome 17q21. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Keratin 19. Immunogen Range: 231-280 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |