Anti-MMP-14 antibody produced in rabbit
SIGMA/SAB4501901 - affinity isolated antibody
Synonym: MATRIX METALLOPROTEINASE 14; MEMBRANE-TYPE; MEMBRANE-TYPE MATRIX METALLOPROTEINASE 1; MT1-MMP; matrix metalloproteinase 14 (membrane-inserted)
Product Type: Chemical
Immunohistochemistry Anti-MMP-14: Cat. No. SAB4501901: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-MMP-14 antibody. Cells on the left were treated with the Anti-MMP-14 antibody. Cells on the right (negative control) were treated with both Anti-MMP-14 antibody and the synthesized immunogen peptide.
Western Blotting Anti-MMP-14: Cat. No. SAB4501901: Immunoblotting analysis of extracts from NIH-3T3 cells, using Anti-MMP-14 antibody. The lane on the left was treated with the Anti-MMP-14 antibody. The lane on the right (negative control) was treated with both Anti-MMP-14 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 65 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P50281  |
| Biochem/physiol Actions: | Matrix metalloproteinase-14 (MMP-14) aids in the migration of leukocytes and breaks down collagen. Migration of cells through the extracellular matrix is also mediated by it. MMP-14 has been shown to be associated with tuberculosis and glioma. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-MMP-14 Antibody detects endogenous levels of total MMP-14 protein. Matrix metalloproteinase-14 (MMP-14) is a collagenase localized to the cell membrane. The gene encoding it is present on human chromosome 14. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MMP-14. Immunogen Range: 471-520 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |