Anti-MMP-15 antibody produced in rabbit
SIGMA/SAB4501903 - affinity isolated antibody
Synonym: MATRIX METALLOPROTEINASE 15; MEMBRANE-TYPE; MEMBRANE-TYPE MATRIX METALLOPROTEINASE 2; MT2-MMP; matrix metalloproteinase 15 (membrane-inserted)
Product Type: Chemical
Western Blotting Anti-MMP-15: Cat. No. SAB4501903: Immunoblotting analysis of extracts from MDA-MB-435 cells, using Anti-MMP-15 antibody. The lane on the left was treated with the Anti-MMP-15 antibody. The lane on the right (negative control) was treated with both Anti-MMP-15 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 75 kDa |
| NCBI accession no. | P51511   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P51511 |
| Biochem/physiol Actions: | Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist. |
| Biochem/physiol Actions: | Matrix metallopeptidase 15 (MMP-15) is implicated in the activation of pro-MMP-2 and pro-MMP-13. It is also facilitates tumor necrosis factor a processing. MMP-15 might promote various types of cancer progression, including non-small cell lung cancer (NSCLC). In addition, it also promotes gastric cancer (GC) invasion and metastasis. Thus, this protein can be used as a potent prognostic marker for GC patients. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-MMP-15 Antibody detects endogenous levels of total MMP-15 protein. |
| General description: | Matrix metallopeptidase 15 (MMP-15) is encoded by the gene mapped to human chromosome l Iq22.2-22.3. The encoded protein belongs to the membrane-type matrix metalloproteinases (MT-MMPs). |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MMP-15. Immunogen Range: 611-660 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |