Anti-MYO1D antibody produced in rabbit
SIGMA/SAB4501947 - affinity isolated antibody
Synonym: KIAA0727; Myosin-Id
Product Type: Chemical
Immunohistochemistry Anti-MYO1D: Cat. No. SAB4501947: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-MYO1D antibody. Cells on the left were treated with the Anti-MYO1D antibody. Cells on the right (negative control) were treated with both Anti-MYO1D antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 116 kDa |
| NCBI accession no. | O94832   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | O94832 |
| Biochem/physiol Actions: | Myosin 1 is involved in cell motility, actin polymerization and vesicular transport.Myosin 1D possess ATPases (adenosine triphosphatase) action, which is inhibited by calcium binding to calmodulin. It is associated with membrane recycling pathway. It is known to be overexpressed during oligodendrocyte myelination. This gene serves as an important biomarker for autism disorder. Myosin 1D maintains cellular growth. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-MYO1D antibody detects endogenous levels of total MYO1D protein.The MYO1D (myosin ID) gene is mapped to human chromosome 17q11. In rats, MYO1D is predominantly expressed in brain. The encoded protein belongs to the short-tailed class I myosin family. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MYO1D. Immunogen Range: 825-874 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |