Anti-OVOL1 antibody produced in rabbit
SIGMA/SAB4502055 - affinity isolated antibody
Synonym: OVOL1; Putative transcription factor Ovo-like 1; hOvo1
Product Type: Chemical
Western Blotting Anti-OVOL1: Cat. No. SAB4502055: Immunoblotting analysis of extracts from K562/A549 cells, using Anti-OVOL1 antibody. The lane on the left was treated with the Anti-OVOL1 antibody. The lane on the right (negative control) was treated with both Anti-OVOL1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 30 kDa |
| NCBI accession no. | O14753   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | O14753 |
| Biochem/physiol Actions: | The protein encoded by the OVOL1 (ovo like transcriptional repressor 1) gene regulates proliferation and differentiation of epithelial cells. This protein is homologous to that in Drosophila species, which regulates trophoblast differentiation. OVOL1 is known to take part in epidermal keratinisation by inducing differentiation. OVOL1 is associated with atopic dermatitis. OVOL1 is associated with skin morphogenesis and tumorigenesis. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-OVOL1 antibody detects endogenous levels of total OVOL1 protein. |
| General description: | The OVOL1 (ovo like transcriptional repressor 1) gene is mapped to human chromosome 11q13.1. It is widely conserved. In mammals, the gene encodes for C2H2 zinc finger transcription factor. It is predominantly expressed in the human placenta and in the inner root sheath of the hair follicle, suprabasal layer of the epidermis, the ductal portion of the eccrine glands and mature sebocytes of the skin.{36] The protein is localized to cytoplasm. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human OVOL1. Immunogen Range: 1-50 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |