Anti-PDGFB antibody produced in rabbit
SIGMA/SAB4502136 - affinity isolated antibody
Synonym: PDGF subunit B; PDGF-2; Platelet-derived growth factor β polypeptide; Platelet-derived growth factor B chain; Platelet-derived growth factor subunit B
Product Type: Chemical
Western Blotting Anti-PDGFB: Cat. No. SAB4502136: Immunoblotting analysis of extracts from NIH-3T3 cells, using Anti-PDGFB antibody. The lane on the left was treated with the Anti-PDGFB antibody. The lane on the right (negative control) was treated with both Anti-PDGFB antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 27 kDa |
| NCBI accession no. | P01127   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P01127 |
| Biochem/physiol Actions: | Platelet derived growth factor receptor β (PDGFRB) acts as a regulator of mesenchymal cells in tumor cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-PDGFB Antibody detects endogenous levels of total PDGFB protein. |
| General description: | The platelet derived growth factor receptor β (PDGFRB) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PDGFB. Immunogen Range: 16-65 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |