Anti-Progesterone Receptor antibody produced in rabbit
SIGMA/SAB4502184 - affinity isolated antibody
Synonym: NR3C3; PGR; PR; PRGR; nuclear receptor 3C3
MDL Number: MFCD00239723
Product Type: Chemical
Immunohistochemistry Anti-Progesterone Receptor: Cat. No. SAB4502184: Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using Anti-Progesterone Receptor antibody. Cells on the left were treated with the Anti-Progesterone Receptor antibody. Cells on the right (negative control) were treated with both Anti-Progesterone Receptor antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-Progesterone Receptor: Cat. No. SAB4502184: Immunofluorescence of A549 cells using Anti-Progesterone Receptor antibody. Cells on the left were treated with the Anti-Progesterone Receptor antibody. Cells on the right (negative control) were treated with both Anti-Progesterone Receptor antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 98 kDa |
| NCBI accession no. | P06401   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | P06401 |
| Application: | Anti-Progesterone receptor antibody produced in rabbit has been used in western blotting and immunohistochemistry. |
| Biochem/physiol Actions: | Progesterone receptor (PR) mediates the actions of progesterone which is essential to maintain pregnancy. PR is known to regulate the genes involved in the process of cell cycle, cell adhesion, invasion, differentiation, proliferation, inflammation, and apoptosis. PR expression might serve as a biomarker in axillary lymph node (ALN) metastasis. Abnormal expression of PR is observed in breast cancer. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Progesterone receptor antibody detects endogenous levels of total progesterone receptor protein. |
| General description: | The progesterone receptor (PR) gene is mapped to human chromosome 11q22–23. The gene encodes for two isoforms, namely PR-A and PR-B, each of which is transcribed from a specific promoter region. The encoded receptor belongs to the family of steroid hormone receptors. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Progesterone Receptor. Immunogen Range: 261-310 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |