Anti-CYTL1 antibody produced in rabbit
SIGMA/SAB4502244 - affinity isolated antibody
Synonym: C4orf4; Cytokine-like protein 1; Protein C17
Product Type: Chemical
Immunohistochemistry Anti-CYTL1: Cat. No. SAB4502244: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-CYTL1 antibody. Cells on the left were treated with the Anti-CYTL1 antibody. Cells on the right (negative control) were treated with both Anti-CYTL1 antibody and the synthesized immunogen peptide.
Western Blotting Anti-CYTL1: Cat. No. SAB4502244: Immunoblotting analysis of extracts from LOVO cells, using Anti-CYTL1 antibody. The lane on the left was treated with the Anti-CYTL1 antibody. The lane on the right (negative control) was treated with both Anti-CYTL1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 15 kDa |
| NCBI accession no. | Q9NRR1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q9NRR1 |
| Biochem/physiol Actions: | In vitro studies reveal that Cytl1 (cytokine like 1) acts as an autocrine or paracrine regulatory factor in the process of cartilage formation. CYTL1, being homologous with IL-2 (interleukin-2), is considered as a potential cytokine that is involved in regulating immune responses. CYTL1 is known to be associated with the pathogenesis of rheumatoid arthritis and osteoarthritis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-CYTL1 antibody detects endogenous levels of total CYTL1 protein. |
| General description: | The CYTL1 (cytokine like 1) gene is mapped to human chromosome 4p16.2. The gene was first discovered in CD34(+) cells of the bone marrow and cord blood. The encoded protein is predominantly expressed in chondrocytes. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CYTL1. Immunogen Range: 61-110 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |