Anti-Peripherin antibody produced in rabbit
SIGMA/SAB4502419 - affinity isolated antibody
Synonym: PERI; PRPH
Product Type: Chemical
Immunohistochemistry Anti-Peripherin: Cat. No. SAB4502419: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-Peripherin antibody. Cells on the left were treated with the Anti-Peripherin antibody. Cells on the right (negative control) were treated with both Anti-Peripherin antibody and the synthesized immunogen peptide.
Western Blotting Anti-Peripherin: Cat. No. SAB4502419: Immunoblotting analysis of extracts from HepG2 cells, using Anti-Peripherin antibody. The lane on the left was treated with the Anti-Peripherin antibody. The lane on the right (negative control) was treated with both Anti-Peripherin antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 53 kDa |
| NCBI accession no. | P41219   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P41219 |
| Biochem/physiol Actions: | Peripherin is known to be associated with the mechanism of organelle transport, function and positioning. It also forms an important part of the cytoskeleton. Mutation in PRPH (peripherin) is observed in amyotrophic lateral sclerosis. Peripherin participates in the elongation of motor axons. Upregulation of PRPH is noticed in neuronal injury. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Peripherin antibody detects endogenous levels of total Peripherin protein. |
| General description: | The PRPH (peripherin) gene is mapped to human chromosome 12q13.12. This gene codes for a 57 kDa intermediate filament protein. Peripherin is predominantly expressed in the peripheral neurons. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Peripherin. Immunogen Range: 421-470 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |