Anti-CXCR7 antibody produced in rabbit
SIGMA/SAB4502446 - affinity isolated antibody
Synonym: CXCR-7; CXCR7; G-protein coupled receptor 159; G-protein coupled receptor RDC1; chemokine orphan receptor 1
Product Type: Chemical
Immunofluorescence Anti-CXCR7: Cat. No. SAB4502446: Immunofluorescence of COS7 cells using Anti-CXCR7 antibody. Cells on the left were treated with the Anti-CXCR7 antibody. Cells on the right (negative control) were treated with both Anti-CXCR7 antibody and the synthesized immunogen peptide.
Western Blotting Anti-CXCR7: Cat. No. SAB4502446: Immunoblotting analysis of extracts from COS7 cells, using Anti-CXCR7 antibody. The lane on the left was treated with the Anti-CXCR7 antibody. The lane on the right (negative control) was treated with both Anti-CXCR7 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 41 kDa |
| NCBI accession no. | P25106   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| immunofluorescence: 1:100-1:500 | |
| western blot: 1:500-1:1000 |
| Biochem/physiol Actions: | CXC- Chemokine receptor 7 (CXCR7) protein interacts with chemokine ligands CXCL11 and CXCL12. This protein shuffles between the plasma membrane and endosomal compartments irrespective of the presence of a ligand such as CXCL11 and 12. CXCR7 protein plays a role in cell survival and cell adhesion to the endothelium. This protein tends to regulate the activity of CXCR4. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-CXCR7 Antibody detects endogenous levels of total CXCR7 protein. |
| General description: | CXC- Chemokine receptor 7 (CXCR7) protein is a seven-transmembrane G-protein coupled receptor (GPCR). It is expressed in the heart tissues, fetal hematopoietic cells, embryonic neuronal, and activated endothelium. CXCR7 gene is mapped on the human chromosome at 2q37.3. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CXCR7. Immunogen Range: 311-360 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |