Anti-GPR126 antibody produced in rabbit
SIGMA/SAB4502469 - affinity isolated antibody
Synonym: GPR126; Probable G-protein coupled receptor 126
Product Type: Chemical
Immunofluorescence Anti-GPR126: Cat. No. SAB4502469: Immunofluorescence of HuvEc cells using Anti-GPR126 antibody. Cells on the left were treated with the Anti-GPR126 antibody. Cells on the right (negative control) were treated with both Anti-GPR126 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 136 kDa |
| NCBI accession no. | Q86SQ4   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 |
| Biochem/physiol Actions: | GPR126 (adhesion G protein-coupled receptor G6) controls the homeostasis of periodontal ligament tissue. GPR126 is responsible for axon myelination of peripheral neurons in human, mice and fish. This gene mediates endothelial cell proliferation and migration, and tube formation, thereby contributing to angiogenesis, which is necessary for overall growth, wound healing and tumor progression. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | G protein-coupled receptor 126 (GPR126) belongs to the adhesion-G protein-coupled receptor (GPCR) family. It is an endothelial cell-enriched gene. The gene is located on human chromosome 6q24.2. |
| General description: | The GPR126 (adhesion G protein-coupled receptor G6) gene codes for a protein that contains an extracellular domain, a seven transmembrane domain at the N-terminal and an intracellular domain in its C-terminal. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GPR126. Immunogen Range: 1091-1140 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |