Anti-Parathyroid Hormone antibody produced in rabbit
SIGMA/SAB4502489 - affinity isolated antibody
Synonym: PTH/PTHr receptor; PTH/PTHrP type I receptor; PTHR1; Parathyroid hormone/parathyroid hormone-related peptide receptor precursor
MDL Number: MFCD01324156
Product Type: Chemical
Western Blotting Anti-Parathyroid Hormone: Cat. No. SAB4502489: Immunoblotting analysis of extracts from A549 cells, using Anti-Parathyroid Hormone antibody. The lane on the left was treated with the Anti-Parathyroid Hormone antibody. The lane on the right (negative control) was treated with both Anti-Parathyroid Hormone antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 12 kDa |
| NCBI accession no. | P01270   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P01270 |
| Biochem/physiol Actions: | PTH (parathyroid hormone) significantly maintains calcium and phosphate homeostasis. The function of PTH is brought about by PTH receptor, a G protein-coupled receptor. Upregulation of PTH is observed in hyperparathyroidism, which leads to hypertension, bone and cardiovascular disease. PTH is also known to improve fracture healing. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Anti-Parathyroid Hormone antibody detects endogenous levels of total parathyroid hormone protein. |
| General description: | The PTH (parathyroid hormone) gene is mapped to human chromosome 11p15.3. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Parathyroid Hormone. Immunogen Range: 51-100 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |