Anti-NF-κB p65 antibody produced in rabbit
SIGMA/SAB4502609 - affinity isolated antibody
Synonym: NFKB3; RELA; TF65; nuclear factor NF-κ-B p65 subunit; p65
MDL Number: MFCD00802848
Product Type: Chemical
Western Blotting Anti-NF-κB p65: Cat. No. SAB4502609: Immunoblotting analysis of extracts from NIH-3T3, using Anti-NF-κB p65 antibody. The lane on the left was treated with the Anti-NF-κB p65 antibody. The lane on the right (negative control) was treated with both Anti-NF-κB p65 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 60 kDa |
| NCBI accession no. | Q04206   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q04206 |
| Application: | Anti-NF-κB p65 antibody produced in rabbit has been used in western blot analysis. |
| Biochem/physiol Actions: | NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) is associated with many fibrotic diseases such as liver fibrosis and cardiac fibrosis. Cell proliferation, inflammation, and apoptosis are some of the processes mediated by NF-κB p65. Dysregulation of the gene results in chronic inflammatory diseases, autoimmune disorders and cancer. NF-κB p65 plays an important role in NF-κB signaling. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-NF-κB p65 antibody detects endogenous levels of total NF-κB p65 protein. |
| General description: | The NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) gene is mapped to human chromosome 11q13.1. It codes for a transcription factor, a subunit of NF-κB. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NF-kappaB p65. Immunogen Range: 278-327 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |