Anti-SMO antibody produced in rabbit
SIGMA/SAB4502822 - affinity isolated antibody
Synonym: Gx protein; SMO
Product Type: Chemical
Western Blotting Anti-SMO: Cat. No. SAB4502822: Immunoblotting analysis of extracts from HuvEc cells, using Anti-SMO antibody. The lane on the left was treated with the Anti-SMO antibody. The lane on the right (negative control) was treated with both Anti-SMO antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 86 kDa |
| NCBI accession no. | Q99835   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q99835 |
| Biochem/physiol Actions: | The SMO (smoothened) gene encodes a protein that mediates hedgehog signaling for embryonic development and to maintain tissue homeostasis. SMO participates in tumor cell proliferation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-SMO antibody detects endogenous levels of total SMO protein. |
| General description: | The SMO (smoothened) gene is mapped to human chromosome 7q32.1. It encodes a protein that belongs to the frizzled family of G protein-coupled receptors. It is a seven transmembrane protein and highly conserved. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SMO. Immunogen Range: 68-117 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |