Anti-SRPK1 antibody produced in rabbit
SIGMA/SAB4502857 - affinity isolated antibody
Synonym: SFRS protein kinase 1; SR-protein-specific kinase 1; Serine/arginine-rich protein-specific kinase 1
Product Type: Chemical
Western Blotting Anti-SRPK1: Cat. No. SAB4502857: Immunoblotting analysis of extracts from K562/RAW264.7 cells, using Anti-SRPK1 antibody. The lane on the left was treated with the Anti-SRPK1 antibody. The lane on the right (negative control) was treated with both Anti-SRPK1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 92 kDa |
| NCBI accession no. | Q96SB4   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q96SB4 |
| Biochem/physiol Actions: | Serine-arginine protein kinase 1 (SRPK1) modulates angiogenesis. Suppressing SRPK1 prevents the development and migration in renal carcinoma cells. In normoxic condition, SRPK1 can increase the migration and invasion of glioma cells. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-SRPK1 Antibody detects endogenous levels of total SRPK1 protein. Serine-arginine protein kinase 1 (SRPK1) belongs to the SR kinase family. In mammals, SRPK1 is expressed in the central nervous system in a region- and neuron-specific manner. This gene is mapped to human chromosome 6p21.2-p21.3. SRPK1 is also expressed in several normal tissues like testis and pancreas. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SRPK1. Immunogen Range: 521-570 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |