Anti-Somatostatin antibody produced in rabbit
SIGMA/SAB4502861 - affinity isolated antibody
Synonym: Growth hormone release-inhibiting factor
Product Type: Chemical
Immunohistochemistry Anti-Somatostatin: Cat. No. SAB4502861: Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Anti-Somatostatin antibody. Cells on the left were treated with the Anti-Somatostatin antibody. Cells on the right (negative control) were treated with both Anti-Somatostatin antibody and the synthesized immunogen peptide.
Western Blotting Anti-Somatostatin: Cat. No. SAB4502861: Immunoblotting analysis of extracts from A549 cells, using Anti-Somatostatin antibody. The lane on the left was treated with the Anti-Somatostatin antibody. The lane on the right (negative control) was treated with both Anti-Somatostatin antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 12 kDa |
| NCBI accession no. | P61278   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P61278 |
| Application: | Anti-Somatostatin, N-Terminal antibody produced in rabbit has been used in immunofluorescence. |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) |
| Biochem/physiol Actions: | Somatostatin plays an important role in regulating the metabolism of other hormones such as growth hormone, insulin, IGF-1 (insulin-like growth factor 1), glucagon, glucagon-like peptide and gastrin. Somatostatin has both regulatory and inhibitory function. It retards gastrointestinal motility and gallbladder contraction, suppresses gut exocrine secretion and reduces epithelial proliferation. Somatostatin is associated with intestinal nutrient absorption and blood flow regulation. This peptide hormone is believed to inhibit cell proliferation and promote apoptosis. Somatostatin acts as a neurotransmitter and neuromodulator. It is associated in maintaining water balance. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Somatostatin antibody detects endogenous levels of total Somatostatin protein. |
| General description: | The SST (somatostatin) gene codes for a peptide hormone containing 14 and 28 amino acid moieties. SST-14 is highly expressed in the central nervous system and peripheral organs. SST-28 is mainly expressed in enteroendocrine cells of the intestine. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Somatostatin. Immunogen Range: 10-59 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |