Anti-CD147, C-Terminal antibody produced in rabbit
SIGMA/SAB4502896 - affinity isolated antibody
Synonym: BASI; CD147; basigin; basigin (Ok blood group); collagenase stimulatory factor
MDL Number: MFCD02262857
Product Type: Chemical
Immunohistochemistry Anti-CD147: Cat. No. SAB4502896: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-CD147 antibody. Cells on the left were treated with the Anti-CD147 antibody. Cells on the right (negative control) were treated with both Anti-CD147 antibody and the synthesized immunogen peptide.
Western Blotting Anti-CD147: Cat. No. SAB4502896: Immunoblotting analysis of extracts from RAW264.7 cells, using Anti-CD147 antibody. The lane on the left was treated with the Anti-CD147 antibody. The lane on the right (negative control) was treated with both Anti-CD147 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 42 kDa |
| NCBI accession no. | P35613   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P35613 |
| Application: | Anti-CD147, C-Terminal antibody has been used in western blotting. |
| Biochem/physiol Actions: | Cluster of differentiation 147 (CD147) is considered as an extracellular matrix metalloproteinase inducer. It participates in several physiological and pathological activities, mainly in tumor invasion and metastasis. CD147 helps in tumor cell-macrophage interactions and stimulates MMPs (matrix metalloproteinases) and vascular endothelial growth factor (VEGF). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-CD147 Antibody detects endogenous levels of total CD147 protein. Cluster of differentiation 147 (CD147) is a multifunctional trans-membrane glycoprotein and is a member of the immunoglobulin superfamily. It occurs in transmembrane and soluble forms. CD147 is also known as EMMPRIN or basigin (BSG). It is a 57 kDa glycoprotein with two extracellular Ig domains. CD147 is located on human chromosome 19p13. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CD147. Immunogen Range: 336-385 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |