Anti-Synapsin1 antibody produced in rabbit
SIGMA/SAB4502903 - affinity isolated antibody
Synonym: Brain protein 4.1; SYN-1; synapsin I
Product Type: Chemical
Immunohistochemistry Anti-Synapsin1: Cat. No. SAB4502903: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-Synapsin1 antibody. Cells on the left were treated with the Anti-Synapsin1 antibody. Cells on the right (negative control) were treated with both Anti-Synapsin1 antibody and the synthesized immunogen peptide.
Western Blotting Anti-Synapsin1: Cat. No. SAB4502903: Immunoblotting analysis of extracts from NIH-3T3 cells, treated with Nocodazole 1ug/ml 16h, using Anti-Synapsin1 antibody. The lane on the left was treated with the Anti-Synapsin1 antibody. The lane on the right (negative control) was treated with both Anti-Synapsin1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 73 kDa |
| NCBI accession no. | P17600   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P17600 |
| Biochem/physiol Actions: | Synapsin I (SYN1) plays an important role in neurotransmitter release, exocytosis of the synaptic vesicles, neurite elongation and synaptogenesis. Brain dysfunction occurs due to improper expression of synapsin I. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Synapsin1 Antibody detects endogenous levels of total Synapsin1 protein. Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. SYN1 is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. It is located in human chromosome Xp11.3. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Synapsin1. Immunogen Range: 26-75 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |