Anti-TAK1 antibody produced in rabbit
SIGMA/SAB4502922 - affinity isolated antibody
Synonym: M3K7; MAP3K7; Mitogen-activated protein kinase kinase kinase 7; TGF-β- activated kinase 1; Transforming growth factor-β-activated kinase 1
MDL Number: MFCD02097469
Product Type: Chemical
Western Blotting Anti-TAK1: Cat. No. SAB4502922: Immunoblotting analysis of extracts from HepG2 cells, using Anti-TAK1 antibody. The lane on the left was treated with the Anti-TAK1 antibody. The lane on the right (negative control) was treated with both Anti-TAK1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 67 kDa |
| NCBI accession no. | O43318   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | O43318 |
| Biochem/physiol Actions: | TAK1 (Transforming growth factor β (TGF-β) activated kinase 1) is activated by TGF-β and other inflammatory stimuli such as chemical and physical agents causing stress, cytokines, and microorganism moieties. TAK1 participates in mitogen-activated protein kinase (MAPK)-p38 signaling pathway. TAK1 is involved in the regulation of osteogenesis. TAK1 is important for productive autophagy. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-TAK1 antibody detects endogenous levels of total TAK1 protein. |
| General description: | The TAK1 (Transforming growth factor β activated kinase 1) gene is mapped to human chromosome 6q15. It encodes for a mitogen-activated protein kinase 7 containing serine-threonine/tyrosine |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human TAK1. Immunogen Range: 161-210 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |