Anti-TGF β2, C-Terminal antibody produced in rabbit
SIGMA/SAB4502956 - affinity isolated antibody
Synonym: Cetermin; G-TSF; Polyergin; TGFB2; Transforming growth factor β-2
MDL Number: MFCD01634324
Product Type: Chemical
Immunohistochemistry Anti-TGF β2: Cat. No. SAB4502956: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-TGF β2 antibody. Cells on the left were treated with the Anti-TGF β2 antibody. Cells on the right (negative control) were treated with both Anti-TGF β2 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| application(s) | research pathology |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 47 kDa |
| NCBI accession no. | P61812   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | P61812 |
| Application: | Anti-TGF β2, C-Terminal antibody produced in rabbit has been used in western blotting. |
| Biochem/physiol Actions: | Transforming growth factor-β2 (TGFB2) protein plays a key role in transforming growth factor-β (TGF-β) signaling pathway. It aids in binding several TGF-β receptors to recruit and stimulate the others against decapentaplegic homolog SMAD protein family. TGF-β2 is involved in the proliferation and metastasis of glioma cells. It is implicated in metabolic syndrome (MetS). Single-nucleotide polymorphisms (SNPs) in TGFB2 are also associated with end-stage renal disease and conotruncal heart defects. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-TGF β2 Antibody detects endogenous levels of total TGF β2 protein. |
| General description: | Transforming growth factor-β2 (TGFB2) gene codes for the transforming growth factor β2 (TGFβ2).( β (TGF-β) protein superfamily. TGFB2 gene is mapped to human chromosome 1q41. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human TGF beta2. Immunogen Range: 361-410 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |