Anti-TGF β Receptor II antibody produced in rabbit
SIGMA/SAB4502960 - affinity isolated antibody
Synonym: TβR-II; TGF-β receptor type II; TGF-β type II receptor; TGFR-2; Transforming growth factor-β receptor type II
Product Type: Chemical
Western Blotting Anti-TGF β Receptor II: Cat. No. SAB4502960: Immunoblotting analysis of extracts from HepG2 (65K) cells, using Anti-TGF β Receptor II antibody. The lane on the left was treated with the Anti-TGF β Receptor II antibody. The lane on the right (negative control) was treated with both Anti-TGF β Receptor II antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 64 kDa |
| NCBI accession no. | P37173   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P37173 |
| Application: | Anti-TGF β Receptor II antibody has been used in immunohistochemistry. |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) |
| Biochem/physiol Actions: | Transforming growth factor β receptor 2 (TGFBR2) plays an important role in signal transduction resulting in mitogenic responses. Mutation in TGFBR2 result in Loeys-Dietz syndrome and Marfan syndrome. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-TGF β Receptor II Antibody detects endogenous levels of total TGF β Receptor II protein. Transforming growth factor β receptor 2 (TGFBR2) is a serine/threonine protein kinase, that belongs to the TGF β receptor subfamily. It is located on human chromosome 3p24. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II. Immunogen Range: 91-140 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |