Anti-WASP antibody produced in rabbit
SIGMA/SAB4503087 - affinity isolated antibody
Synonym: IMD2; WAS; Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome protein homolog
Product Type: Chemical
Immunohistochemistry Anti-WASP: Cat. No. SAB4503087: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-WASP antibody. Cells on the left were treated with the Anti-WASP antibody. Cells on the right (negative control) were treated with both Anti-WASP antibody and the synthesized immunogen peptide.
Western Blotting Anti-WASP: Cat. No. SAB4503087: Immunoblotting analysis of extracts from HepG2 cells, using Anti-WASP antibody. The lane on the left was treated with the Anti-WASP antibody. The lane on the right (negative control) was treated with both Anti-WASP antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 52 kDa |
| NCBI accession no. | P42768   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P42768 |
| Biochem/physiol Actions: | WASP (Wiskott-Aldrich syndrome protein) is regarded as a scaffold protein that integrates cell surface signals to actin cytoskeleton. WASP gene regulates actin polymerization, contributing to T-cell activation and migration. Neural WASP is known to regulate a variety of cellular processes including pathogen infection, vesicle trafficking, invadopodium formation and growth, and neurite extension. Mutation in this gene causes WAS, a X-linked recessive immunodeficiency disorder. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-WASP Antibody detects endogenous levels of total WASP protein. |
| General description: | WASP (Wiskott-Aldrich syndrome protein) codes for a 65 kDa protein, localized to the cytoplasm. The WASP gene is mapped to human chromosome Xp11.23. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human WASP. Immunogen Range: 256-305 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |