Anti-FZD5 antibody produced in rabbit
SIGMA/SAB4503132 - affinity isolated antibody
Synonym: FZD5; Frizzled-5; Fz-5; FzE5; hFz5
Product Type: Chemical
Immunohistochemistry FZD5 Antibody: Cat. No. SAB4503132: Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FZD5 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence Anti-FZD5: Cat. No. SAB4503132: Immunofluorescence of COS7 cells using Anti-FZD5 antibody. Cells on the left were treated with the Anti-FZD5 antibody. Cells on the right (negative control) were treated with both Anti-FZD5 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 64 kDa |
| NCBI accession no. | Q13467   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:5000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | Q13467 |
| Biochem/physiol Actions: | Fzd5 (frizzled class receptor 5) is a receptor component for the canonical and non-canonical Wnt signaling pathways which is necessary for cell proliferation and cell differentiation. Fzd5 might serve as an important biomarker for eye malformation. The Wnt5a-Fz5 complex is known to support the functions of innate immunity. Fzd5 along with Gcm1 (chorion-specific transcription factor) is involved in a feedback mechanism that regulates trophoblast differentiation and chorionic branching in placenta. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-FZD5 Antibody detects endogenous levels of total FZD5 protein. |
| General description: | The FZD5 (frizzled class receptor 5) gene encodes a receptor FZ5 for Wnt proteins and is mapped to human chromosome 2q33.3. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FZD5. Immunogen Range: 31-80 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |