Anti-USP42 antibody produced in rabbit
SIGMA/SAB4503327 - affinity isolated antibody
Synonym: Deubiquitinating enzyme 42; USP42; Ubiquitin carboxyl-terminal hydrolase 42; Ubiquitin thioesterase 42; Ubiquitin-
Product Type: Chemical
Western Blotting Anti-USP42: Cat. No. SAB4503327: Immunoblotting analysis of extracts from HT-29 cells, using Anti-USP42 antibody. The lane on the left was treated with the Anti-USP42 antibody. The lane on the right (negative control) was treated with both Anti-USP42 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 145 kDa |
| NCBI accession no. | Q9H9J4   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q9H9J4 |
| Application: | Anti-USP42 antibody produced in rabbit is suitable for indirect ELISA and western blot applications. |
| Biochem/physiol Actions: | USP42 (ubiquitin specific peptidase 42) is a nuclear protein belonging to the ubiquitin-specific protease (USP) family. It is widely distributed in human tissues, especially in skeletal muscle and testis. It is involved in the regulation of ubiquitin-mediated pathways. It exerts deubiquitylating activity by cleaving ubiquitin from an ubiquitin-β-galactosidase fusion protein. It plays an important role in the regulation of p53 activity. It helps to stabilize p53 in response to stress and promotes early activation of p53. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-USP42 Antibody detects endogenous levels of total USP42 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human USP42. Immunogen Range: 251-300 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |