Anti-FGF18 antibody produced in rabbit
SIGMA/SAB4503479 - affinity isolated antibody
Synonym: FGF-18; Fibroblast growth factor 18; Zfgf5
Product Type: Chemical
Immunohistochemistry Anti-FGF18: Cat. No. SAB4503479: Immunohistochemistry analysis of paraffin-embedded human heart tissue using Anti-FGF18 antibody. Cells on the left were treated with the Anti-FGF18 antibody. Cells on the right (negative control) were treated with both Anti-FGF18 antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-FGF18: Cat. No. SAB4503479: Immunofluorescence of HuvEc cells using Anti-FGF18 antibody. Cells on the left were treated with the Anti-FGF18 antibody. Cells on the right (negative control) were treated with both Anti-FGF18 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 23 kDa |
| NCBI accession no. | O76093   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | O76093 |
| Biochem/physiol Actions: | FGF18 (fibroblast growth factor 18) plays an important role in the skeletal development of the embryonic and adult organism. It is associated with colorectal and ovarian cancer. FGF18 participates in cell proliferation and differentiation during osteogenesis and chondrogenesis. It is essential for the growth of bone, cartilage, hair, cardiovasculature and alveolus. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein. FGF18 (fibroblast growth factor 18) is a member of the paracrine-acting FGF8 subfamily. It is expressed in the perichondrium and joints of developing long bones. FGF18 is a 21.2 kDa glycosylated secretory protein, that is structurally similar to FGF8 and FGF17. It is mapped to human chromosome 5q35.1. Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FGF18. Immunogen Range: 151-200 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |