Anti-CD40 antibody produced in rabbit
SIGMA/SAB4503674 - affinity isolated antibody
Synonym: B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40
Product Type: Chemical
Immunohistochemistry Anti-CD40: Cat. No. SAB4503674: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-CD40 antibody. Cells on the left were treated with the Anti-CD40 antibody. Cells on the right (negative control) were treated with both Anti-CD40 antibody and the synthesized immunogen peptide.
Western Blotting Anti-CD40: Cat. No. SAB4503674: Immunoblotting analysis of extracts from COS7 cells, using Anti-CD40 antibody. The lane on the left was treated with the Anti-CD40 antibody. The lane on the right (negative control) was treated with both Anti-CD40 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 30 kDa |
| NCBI accession no. | P25942   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:10000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P25942 |
| Application: | Anti-CD40, C-Terminal antibody has been used in western blotting. |
| Biochem/physiol Actions: | Cluster of differentiation 40 (CD40) plays a major role in cellular and humoral immunity. It initiates inflammatory response to induce the progression of atherosclerosis.The CD40 pathway participates in the growth and pathogenesis of autoimmune diseases like rheumatoid arthritis (RA). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-CD40 Antibody detects endogenous levels of total CD40 protein. |
| General description: | Cluster of differentiation 40 (CD40) is a type I transmembrane glycoprotein. It has a molecular weight of 40 ~ 50kDa and made of 277 amino acids. The CD40 gene is mapped to human chromosome 20q11-13. It has eight introns and nine exons. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CD40. Immunogen Range: 228-277 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |