Anti-phospho-SYK (pTyr348) antibody produced in rabbit
SIGMA/SAB4503838 - affinity isolated antibody
Synonym: Anti-IMD82; Anti-p72-Syk
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma.
Immunohistochemistry Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: Immunohistochemistry analysis of paraffin-embedded Human Non-Hodgkin′s lymphoma.
Immunohistochemistry Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: Immunohistochemistry analysis of paraffin-embedded Human ovary carcinoma.
Immunohistochemistry Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: Immunohistochemistry analysis of paraffin-embedded Human stomach carcinoma.
Immunohistochemistry Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: Immunohistochemistry analysis of paraffin-embedded Human tonsil.
Western Blotting Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: Western blot analysis of extracts from COS-7 cells treated with 200 ng/mL EGF for 30 minutes.
ELISA Anti-phoshpho-SYK (pTyr348): Cat. No. SAB4503838: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 72 kDa |
| NCBI accession no. | P43405   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr348) |
| technique(s) | ELISA: 1:10000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P43405 |
| Biochem/physiol Actions: | Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells.It participates in B-cell receptor signaling.This protein helps to phosphorylate the α-tubulin subunits of microtubules. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells.SYK is mapped to human chromosome 9q22. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348. Immunogen Range: 314-363 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |