Anti-phospho-CD4 (pSer433) antibody produced in rabbit
SIGMA/SAB4504134 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: Immunohistochemistry analysis of paraffin-embedded Human brain gliomas.
Immunohistochemistry Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma.
Immunohistochemistry Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: Immunohistochemistry analysis of paraffin-embedded Human Non-Hodgkin′s lymphoma.
Immunohistochemistry Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: Immunohistochemistry analysis of paraffin-embedded Human ovary carcinoma.
Immunohistochemistry Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: Immunohistochemistry analysis of paraffin-embedded Human prostate carcinoma.
Immunohistochemistry Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: Immunohistochemistry analysis of paraffin-embedded Human prostate carcinoma.
ELISA Anti-phoshpho-CD4 (pSer433): Cat. No. SAB4504134: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 51 kDa |
| NCBI accession no. | P01730   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer433) |
| technique(s) | ELISA: 1:40000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | P01730 |
| Biochem/physiol Actions: | CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serves as a primary receptor for HIV-1 entry. Individuals with infectious and chronic inflammatory diseases shows higher level of soluble CD4 (sCD4). |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31. CD4 belongs to the immunoglobulin superfamily (IgSF). It has four extracellular Ig-like domains, a hydrophobic transmembrane region and a 40-residue cytoplasmic tail. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CD4 around the phosphorylation site of Ser433. Immunogen Range: 401-450 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |