Anti-phospho-CXCR4 (pSer339) antibody produced in rabbit
SIGMA/SAB4504153 - affinity isolated antibody
Synonym: Anti-CD184; Anti-D2S201E; Anti-FB22; Anti-HM89; Anti-HSY3RR; Anti-LAP-3; Anti-LAP3; Anti-LCR1; Anti-LESTR; Anti-NPY3R; Anti-NPYR; Anti-NPYRL; Anti-NPYY3R; Anti-WHIM; Anti-WHIMS; Anti-WHIMS1
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma.
Immunohistochemistry Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma.
Immunohistochemistry Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: Immunohistochemistry analysis of paraffin-embedded Human liver carcinoma.
Immunohistochemistry Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: Immunohistochemistry analysis of paraffin-embedded Human prostate carcinoma.
Immunohistochemistry Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: Immunohistochemistry analysis of paraffin-embedded Human prostate carcinoma.
Western Blotting Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: Western blot analysis of extracts from HuvEc cells treated with 25 μM Etoposide for 24 hours.
ELISA Anti-phoshpho-CXCR4 (pSer339): Cat. No. SAB4504153: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 39 kDa |
| NCBI accession no. | P61073   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer339) |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P61073 |
| Application: | Anti-phospho-CXCR4 (pSer339) antibody has been used in immunohistochemical analysis. |
| Biochem/physiol Actions: | The CXC chemokine receptor 4 (CXCR4) participates in the progression of the embryo, immune and inflammatory responses, modulation of hematopoiesis, human immunodeficiency virus infection and stimulation of angiogenesis. CXCR4 and its ligand, CXCL12 is involved in the synthesis of B-cell, myelopoiesis, integrin activation and chemotaxis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The CXC chemokine receptor 4 (CXCR4) is a G-protein coupled 7-transmembrane (TM) chemokine receptor. It is made up of 352 amino acids. CXCR4 is expressed on the surface of T-cells, B-cells, monocytes, neutrophils and dendritic cells. This gene is located on human chromosome 2q22.1. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339. Immunogen Range: 303-352 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |