Anti-phospho-CDK5 (pTyr15) antibody produced in rabbit
SIGMA/SAB4504276 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-CDK5 (pTyr15): Cat. No. SAB4504276: Immunohistochemistry analysis of paraffin-embedded Human ovary carcinoma.
Immunohistochemistry Anti-phoshpho-CDK5 (pTyr15): Cat. No. SAB4504276: Immunohistochemistry analysis of paraffin-embedded Human stomach carcinoma.
Western Blotting Anti-phoshpho-CDK5 (pTyr15): Cat. No. SAB4504276: Western blot analysis of extracts from COS-7 cells treated with 200 ng/mL EGF for 30 minutes and HEK 293 cells treated with 100 μM H2O2 for 15 minutes.
ELISA Anti-phoshpho-CDK5 (pTyr15): Cat. No. SAB4504276: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 33 kDa |
| NCBI accession no. | Q00535   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr15) |
| technique(s) | ELISA: 1:5000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q00535 |
| Biochem/physiol Actions: | Cyclin-dependent kinase 5 (CDK5) controls migration and neuronal plasticity. This protein participates in neuron migration, neurite outgrowth and support and synaptogenesis. It also helps in the development of lymphatic vessels. Suppressing Cdk5 promotes cell death of tumor-initiating cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Cyclin-dependent kinase 5 (CDK5) belongs to the CDKs family. Active CDK5 is present in pancreatic β cells, corneal epithelial cells and monocytes. This gene is mapped to human chromosome 7q36. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CDK5 around the phosphorylation site of Tyr15. Immunogen Range: 1-50 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |