Anti-phospho-eIF2 α (pSer51) antibody produced in rabbit
SIGMA/SAB4504388 - affinity isolated antibody
Synonym: Anti-EIF-2; Anti-EIF-2A; Anti-EIF-2alpha; Anti-EIF2; Anti-EIF2A
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human kidney carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human liver carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human Non-Hodgkin′s lymphoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human ovary carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human ovary carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human prostate carcinoma.
Immunohistochemistry Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue.
Western Blotting Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: Western blot analysis of extracts from K562 cells treated with 1000 U/mL IFN-α for 18 hours.
ELISA Anti-phoshpho-eIF2 α (pSer51): Cat. No. SAB4504388: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 36 kDa |
| NCBI accession no. | P05198   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer51) |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P05198 |
| Application: | Anti-phospho-eIF2 α(pSer51) antibody has been used in western blotting and immunohistochemistry. |
| Biochem/physiol Actions: | EIF2S1 (eukaryotic translation initiation factor 2 subunit α) acts as a modulator in apoptosis signaling pathway . During endoplasmic reticulum stress, eIF2α plays a major role in signaling pathways in the development of tumor . |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | EIF2S1 (eukaryotic translation initiation factor 2 subunit α) is a heterotrimeric protein and a regulatory subunit of eIF2 . eIF2 has three general subunits- α, βand γ . eIF2α is located on human chromosome 14q23 . |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Ser51. Immunogen Range: 21-70 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |