Anti-phospho-p53 (pSer15) antibody produced in rabbit
SIGMA/SAB4504499 - affinity isolated antibody
Synonym: Anti-BCC7; Anti-BMFS5; Anti-LFS1; Anti-P53; Anti-TRP53
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-p53 (pSer15): Cat. No. SAB4504499: Immunohistochemistry analysis of paraffin-embedded Human liver carcinoma.
Immunohistochemistry Anti-phoshpho-p53 (pSer15): Cat. No. SAB4504499: Immunohistochemistry analysis of paraffin-embedded Human Non-Hodgkin′s lymphoma.
Western Blotting Anti-phoshpho-p53 (pSer15): Cat. No. SAB4504499: Western blot analysis of extracts from HeLa cells treated with HU.
ELISA Anti-phoshpho-p53 (pSer15): Cat. No. SAB4504499: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 43 kDa |
| NCBI accession no. | P04637   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer15) |
| technique(s) | ELISA: 1:10000 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P04637 |
| Biochem/physiol Actions: | TP53 (tumor protein p53) gene is required for the DNA-damage checkpoint.This protein controls cell cycle, senescence and apoptosis upon oncogene activation, stress and DNA damage. Mutation in TP53 results in breast cancer. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | TP53 (tumor protein p53) gene is located on human chromosome 17p13.1. This is a tumor-suppressor gene. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human p53 around the phosphorylation site of Ser15. Immunogen Range: 1-50 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |