Anti-phospho-Bax (pSer184) antibody produced in rabbit
SIGMA/SAB4504690 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-Bax (pSer184): Cat. No. SAB4504690: Immunohistochemistry analysis of paraffin-embedded Human brain gliomas.
Immunohistochemistry Anti-phoshpho-Bax (pSer184): Cat. No. SAB4504690: Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma.
Immunohistochemistry Anti-phoshpho-Bax (pSer184): Cat. No. SAB4504690: Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma.
Immunohistochemistry Anti-phoshpho-Bax (pSer184): Cat. No. SAB4504690: Immunohistochemistry analysis of paraffin-embedded Human liver carcinoma.
Immunohistochemistry Anti-phoshpho-Bax (pSer184): Cat. No. SAB4504690: Immunohistochemistry analysis of paraffin-embedded Human prostate carcinoma.
ELISA Anti-phoshpho-Bax (pSer184): Cat. No. SAB4504690: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 21 kDa |
| NCBI accession no. | Q07812   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer184) |
| technique(s) | ELISA: 1:10000 |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | Q07812 |
| Biochem/physiol Actions: | Bif-1 (BAX-interacting factor 1) plays a vital role in apoptosis. BAX gene may act as a negative regulator of autophagy in CRC (Colorectal cancer) development. Lack of Bif-1 affects lipid homeostasis and results in obesity followed by insulin resistance. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Bif-1 (BAX-interacting factor 1), a membrane-curvature inducing protein is located on human chromosome 19q13. Bif-1 is also known as SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1)/ Endophilin B1. It belongs to the membrane curvature-driving endophilin protein family. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184. Immunogen Range: 143-192 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |