Monoclonal Anti-CD48 antibody produced in mouse
SIGMA/SAB4700192 - clone MEM-102, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-BLAST-1
Product Type: Chemical
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| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | MEM-102, monoclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG1 |
| NCBI accession no. | NM_001778.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | nonhuman primates, human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| UniProt accession no. | P09326 |
| Application: | The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. |
| Biochem/physiol Actions: | Cluster of differentiation 48 (CD48) acts as an adhesion and co-stimulatory molecule and stimulates various effects in B and T lymphocytes, natural killer cells, mast cells and eosinophils. CD48 interacts with its ligand CD2 and other molecules and promotes rearrangement of signaling factors in lipid rafts, Lck-kinase activity and tyrosine phosphorylation. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Cluster of differentiation 48 (CD48) molecule, also known as BLAST1, is encoded by the gene mapped to human chromosome 1q23.3. CD48 is a glycosyl-phosphatidyl-ino |
| General description: | The antibody MEM-102 reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes. |
| Immunogen: | Raji human Burkitt′s lymphoma cell line |
| Physical form: | Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |