Monoclonal Anti-CD79A antibody produced in mouse
SIGMA/SAB4700229 - clone HM47, purified immunoglobulin, buffered aqueous solution
Product Type: Chemical
Flow cytometry Monoclonal Anti-CD79A: Cat. No. SAB4700229: Flow cytometry analysis of Human, Canine and Porcine B lymphocytes with Anti-CD79a and Anti-CD20 antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | HM47, monoclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG1 |
| NCBI accession no. | NM_001783.3   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | pig, human, mouse |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| UniProt accession no. | P11912 |
| Application: | The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. |
| Biochem/physiol Actions: | Cluster of differentiation 79A (CD79A) functions as a highly lineage-specific marker of B lymphoid cells. It also plays a crucial role in the diagnosis of acute leukemia. Mutations in the gene might be a cause of agammaglobulinemia. CD79A acts as an potential biomarker for the detection of B lineage neoplasms. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Cluster of differentiation 79A (CD79A), also known as mb-1 gene, is encoded by the gene mapped to human chromosome 19q13.2-13.3. The encoded protein is characterized with a single extracellular immunoglobulin domain, a transmembrane domain and an intracytoplasmic signaling domain with an immunoreceptor tyrosine-based activation motif (ITAM). |
| General description: | The antibody HM47 interacts with CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms. |
| Immunogen: | Synthetic peptide corresponding to amino acids 208-222 of human CD79a |
| Physical form: | Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |