Monoclonal Anti-CD15 antibody produced in mouse
SIGMA/SAB4700284 - clone MEM-158, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-FUT4; Anti-Lewis x Blood Group antigen
Product Type: Chemical
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| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | MEM-158, monoclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgM |
| NCBI accession no. | NM_002033.3   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| UniProt accession no. | P22083 |
| Application: | The reagent is designed for Flow Cytometry analysis using 10 μL reagent / 100 μL of sample. |
| Biochem/physiol Actions: | Cluster of differentiation 15 (CD15)/fucosyltransferase 4 catalyzes the synthesis of Lex on the surface of the proliferating cells, in organ buds progressing in mesenchyma, during human embryogenesis. Overexpression of the gene has been associated with development of various type of cancers such as colon cancer, pancreatic cancer, gastric cancer and lung adenocarcinoma. siRNAs of FUT1/4 can be used as a potent therapeutic agent in human LeY-expressing cancers. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Cluster of differentiation 15 (CD15), also known as fucosyltransferase 4 (FUT4)/ Lewis x blood group antigen, is encoded by the gene mapped to long arm of human chromosome 11q21. It is ubiquitously expressed in various tissues such as gastrointestinal tract, brain and leukocytes. |
| General description: | The antibody MEM-158 reacts with CD15, a cell membrane molecule 3-fucosyl-N-acetyllactosa |
| Immunogen: | Human granulocytes |
| Physical form: | Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |