Monoclonal Anti-KRT18-FITC antibody produced in mouse
SIGMA/SAB4700672 - clone DC-10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-Cytokeratin 18
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | DC-10, monoclonal |
| concentration | 0.1 mg/mL |
| conjugate | FITC conjugate |
| form | buffered aqueous solution |
| isotype | IgG1 |
| NCBI accession no. | NM_000224.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| UniProt accession no. | P05783 |
| Application: | The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5-10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. |
| Biochem/physiol Actions: | Keratins help to maintain the structural integrity. They also control Fas‐mediated apoptosis and regulate cell size and protein synthesis. Keratin 18 plays a major role in the development of lung cancer. It acts as a therapeutic target for non-small cell lung cancer (NSCLC). |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Keratin 18/cytokeratin 18 (CK18) is a structural protein. It is present in single-layer epithelia. It is located on human chromosome 12q13. |
| General description: | The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues. |
| Immunogen: | Human breast carcinoma cell line PMC-42 |
| Physical form: | Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |