Monoclonal Anti-CD3-APC antibody produced in mouse
SIGMA/SAB4701098 - clone APA1/1
Synonym: CD3 epsilon chain; CD3epsilon; IMD18; T3E
Product Type: Chemical
accession no. | BC049847 |
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | APA1/1, monoclonal |
concentration | 0.1 mg/mL |
conjugate | Allophycocyanin conjugate |
form | buffered aqueous solution |
shipped in | wet ice |
storage temp. | 2-8°C |
technique(s) | flow cytometry: 1.5 μg/mL |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation. |
Immunogen: | Purified human CD3 proteins isolated from thymus |
Physical form: | Solution in phosphate buffered saline with 15 mM sodium azide. |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352203 |